Summary
Sensing he has little time left, Jin resolves to pass on his entire medical knowledge to the Jinyudo doctors. Kyotaro makes a difficult decision.
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Two years have passed since the last season. Jin and Saki develop a sweet confectionery that contains medicine for Saki's mother who has a severe case of beriberi. Meanwhile, Ryoma asks Jin to care for Kaishuu Katsu's mentor, Shozan Sakuma. Shozan is in a critical state after being attacked by the Shinsengumi. Jin is reluctant because curing Shozan would mean changing the course of history. However, Shozan tells him that he too is involved in the “present”.
Two years have passed since the last season. Jin and Saki develop a sweet confectionery that contains medicine for Saki's mother who has a severe case of beriberi. Meanwhile, Ryoma asks Jin to care for Kaishuu Katsu's mentor, Shozan Sakuma. Shozan is in a critical state after being attacked by the Shinsengumi. Jin is reluctant because curing Shozan would mean changing the course of history. However, Shozan tells him that he too is involved in the “present”.
Sensing he has little time left, Jin resolves to pass on his entire medical knowledge to the Jinyudo doctors. Kyotaro makes a difficult decision.
Jin, Saki and Saburi perform a major surgery to try and save Ryoma’s life. The Jinyudo doctors face charges of teaching how to create fake penicillin.
As Jin rushes to Kyoto with Saki and Saburi to prevent Ryoma’s assassination, Kyotaro heads for the same destination with a very different mission.
As Ryoma fully devotes himself to achieving a return to imperial rule, Jin battles to protect the lives of both a struggling Nokaze and her child.
After receiving a wedding invitation from Nokaze, Saki and Jin go to Yokohama for the occasion. But during the visit, Nokaze wants Jin to examine her.
While visiting Nagasaki to teach other doctors about penicillin, Jin catches up with Ryoma but senses that something about him has changed.
Jin does all he can to help a renowned kabuki actor suffering from severe lead poisoning and limb paralysis to perform on stage one last time.
As the Jinyudo doctors continue trying to create penicillin in powder form, Taki asks Jin for help in treating a noblewoman from an important family.
Locked away in prison for a crime he didn’t commit, Jin endures harsh conditions and torture. Ryoma and Kyotaro fight to prove his innocence.
Jin considers the risks of interfering with history by treating an imperial princess with suspected beriberi. An old acquaintance appears before him.
Jin examines Saki’s ill mother after learning that she may have beriberi disease due to malnutrition. Ryoma arrives from Kyoto seeking Jin’s help.
The story follows a brain surgeon named Minakata Jin who has spent the last two years in anguish, as his fiancee lies in a vegetative state after an operation he performed. One day, he faints at the hospital and awakens to find himself transported back in time to the Edo Period. He is soon attacked by a samurai, but he escapes with the help of a man named Kyotaro. Kyotaro suffers a serious injury to the head while trying to protect him, but Jin manages to save his life despite a lack of proper medical equipment. Because of that, Kyotaro's sister Saki begins taking an interest in Jin and becomes his assistant. Meanwhile, Jin is determined to find a way back to the present.
The story follows a brain surgeon named Minakata Jin who has spent the last two years in anguish, as his fiancee lies in a vegetative state after an operation he performed. One day, he faints at the hospital and awakens to find himself transported back in time to the Edo Period. He is soon attacked by a samurai, but he escapes with the help of a man named Kyotaro. Kyotaro suffers a serious injury to the head while trying to protect him, but Jin manages to save his life despite a lack of proper medical equipment. Because of that, Kyotaro's sister Saki begins taking an interest in Jin and becomes his assistant. Meanwhile, Jin is determined to find a way back to the present.
Jin wonders whether Ryoma might have traveled into the future during their tumble from the cliff. Saburi and Jin reexamine Nokaze’s symptoms together.
When Jin visits Yoshiwara to examine Nokaze before her impending marriage, he notices something concerning during the exam but chooses to stay silent.
With both Nokaze and Saki developing strong romantic feelings for Jin, bells ring out across Edo warning of a dangerous fire engulfing the city.
Nokaze asks Jin to treat a sick courtesan, but he needs stronger penicillin to cure her. Kyotaro gets an idea to secure the funds required to make it.
When Jin learns of a patient with a terrible burn, he wants to help her. But the treatment requires a skin graft and a large amount of penicillin.
While visiting an eminent doctor of traditional medicine, Jin is pressed about his medical background — and soon gets an opportunity to prove himself.
Jin takes on the ambitious task of producing penicillin to help Nokaze’s sister, a patient suffering terribly during the final stage of syphilis.
Jin meets a courtesan with a striking resemblance to his fiancée in present-day Tokyo. She asks him to perform a life-saving operation on her father.
Just as Jin learns the shogunate will support his efforts to treat cholera patients with new techniques, he suddenly shows signs of infection.
As Jin struggles to process the startling reality of his situation, a resurgence of a mysterious illness frightens residents across the city of Edo.
Suddenly finding himself in the Edo period, neurosurgeon Jin Minakata tries to return to the present day. But an oddly familiar stranger intervenes.
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