Series synopsis
Grey's Anatomy is an American drama television series that premiered on ABC on March 27, 2005. It was created by Shonda Rhimes. It stars Ellen Pompeo, Chandra Wilson, Sandra Oh and Justin Chambers.
Follows the personal and professional lives of a group of doctors at Seattle's Grey Sloan Memorial Hospital.
Premise
Follows the personal and professional lives of a group of doctors at Seattle's Grey Sloan Memorial Hospital.
Premise: Begin again.
Cast and characters
Leading cast
- Ellen Pompeo as Meredith Grey
- Chandra Wilson as Miranda Bailey
- Sandra Oh as Cristina Yang
- Justin Chambers as Alex Karev
- James Pickens Jr. as Richard Webber
- Patrick Dempsey as Derek Shepherd
- Caterina Scorsone as Amelia Shepherd
- Camilla Luddington as Jo Wilson
Supporting cast
- Kevin McKidd as Owen Hunt
- Katherine Heigl as Izzie Stevens
- Kim Raver as Teddy Altman
- Sara Ramirez as Callie Torres
- Jessica Capshaw as Arizona Robbins
- Jason George as Ben Warren
- Eric Dane as Mark Sloan
- Chris Carmack as Atticus Lincoln
- Chyler Leigh as Lexie Grey
- Anthony Hill as Winston Ndugu
- Jesse Williams as Jackson Avery
- Adelaide Kane as Jules Millin
Guest cast
- Brooke Smith as Erica Hahn
- Paul Adelstein as Dr. Cooper Freedman
- Jurnee Smollett as Beth Monroe
- Keith David as Lloyd Mackie
- Diahann Carroll as Jane Burke
- Chris O'Donnell as Finn Dandridge
- Bruce Weitz as Edward Levangie
- Arija Bareikis as Savannah
- Donovan Leitch as Rick Friart
- Curtis Armstrong as Robert Martin
- Demi Lovato as Hayley May
- Kathryn Joosten as Stephanie Drake
Episodes
This series spans 20 seasons with 487 episodes.
| Season | Episodes | First aired | Last aired |
|---|---|---|---|
| Season 0 | 68 | February 14, 2006 | August 29, 2017 |
| Season 1 | 9 | March 27, 2005 | May 22, 2005 |
| Season 2 | 27 | September 25, 2005 | May 15, 2006 |
| Season 3 | 25 | September 21, 2006 | May 17, 2007 |
| Season 4 | 17 | September 27, 2007 | May 22, 2008 |
| Season 5 | 24 | September 25, 2008 | May 14, 2009 |
| Season 6 | 24 | September 24, 2009 | May 20, 2010 |
| Season 7 | 22 | September 23, 2010 | May 19, 2011 |
| Season 8 | 24 | September 22, 2011 | May 17, 2012 |
| Season 9 | 24 | September 27, 2012 | May 16, 2013 |
| Season 10 | 24 | September 26, 2013 | May 15, 2014 |
| Season 11 | 24 | September 25, 2014 | May 14, 2015 |
| Season 12 | 24 | September 24, 2015 | May 19, 2016 |
| Season 13 | 24 | September 22, 2016 | May 18, 2017 |
| Season 14 | 24 | September 28, 2017 | May 17, 2018 |
| Season 15 | 25 | September 27, 2018 | May 16, 2019 |
| Season 16 | 21 | September 26, 2019 | April 9, 2020 |
| Season 17 | 17 | November 12, 2020 | June 3, 2021 |
| Season 18 | 20 | September 30, 2021 | May 26, 2022 |
| Season 19 | 20 | October 6, 2022 | May 18, 2023 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
S1 - Alternative Title Track A completely different intro sequence that was created during early production—not used in the final show. More stylized and abstract, sometimes referred to by fans as the “blue anatomy” version. Features different music and a more dramatic tone. Sometimes called "Grey's Anatomy Avant-Garde Intro" on fan forums. |
February 14, 2006 |
| 2 |
S1 - Anatomy of a Pilot Behind-the-scenes of the pilot episode. |
February 14, 2006 |
| 3 |
S1 - Avant-garde Trailer Experimental Trailer: A stylized promotional video created before the show aired. Very different from the final tone—dark, edgy, almost indie-film-like. Uses haunting music and dramatic editing, highlighting the emotional stakes and interpersonal tension rather than the medical drama. Included on some international Season 1 DVDs or as an Easter egg. |
February 14, 2006 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
A Hard Day's Night Meet Meredith Grey. Daughter of famous surgeon Ellis Grey and currently recovering from a one-night stand. She shoos away her evening's companion, saying she'll be late for her first day of work. She is a first year intern at Seattle Grace Hospital and is working alongside some colorful characters. Cristina Yang is a highly competitive Stanford graduate who befriends Meredith. George O'Malley is a quirky warm hearted man who learns a lesson or two on his first day. Izzie Stevens is a former model who doesn't get any special treatment on her first day. And Alex Karev is an arrogant jerk who misdiagnoses a patient on his first shift. Overseeing them is Miranda Bailey, (not-so-) affectionately dubbed 'The Nazi'. Meredith also gets a surprise when she realizes that her friend from the night before is a co-worker, and even worse, her boss. |
March 27, 2005 |
| 2 |
The First Cut is the Deepest The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile Meredith puts her career on the line to save a newborn in the hospital nursery, and the other interns learn that it takes more than just medical knowledge to be good at their jobs. |
April 3, 2005 |
| 3 |
Winning a Battle, Losing the War A bike race injures several pedestrians as well as well as participants. One pedestrian is left brain dead. Christina and Issie wish to use his organs for organ donation but with Christina's detachment and Issie's ever hopeful attitude that the man will recover, they will find the organ harvesting process an emotional one. Preston faces feelings of his dislike of organ harvesting - as a surgeon, he likes saving lives; harvesting organs doesn't save the person's life. George deals with Mac, a friend of the chief, who won't stop flirting with him. He is in need of a new liver. Meredith is fed up with Alex showing off as she continues trying to push Derek away. She also is reaching the limits of Issie's sunshine and George's politeness as she goes on living with them. Then there is their desire to see Meredith's mother's medical tapes. Getting through the day, Meredith realizes the keys to winning the race. |
April 10, 2005 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Raindrops Keep Falling on My Head Picks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is pimped out to relay the hospital gossip back to Webber. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Cristina ponders her relationship with Burke while trying to make a decision. Meredith is devastated by the latest blow to her love life. Meanwhile, Joe the bartender collapses. |
September 25, 2005 |
| 2 |
Enough Is Enough There's tension between Meredith and Addison. We find out why Derek and Addison aren't together. Bailey puts George on an impossible case. The rest of the interns operate on a family that was just in a car accident. |
October 2, 2005 |
| 3 |
Make Me Lose Control Cristina and Meredith try to figure out if Cristina should tell Burke that she's pregnant right before Cristina faces an emergency. Alex and Izzie get closer while Meredith's mother gets too close. |
October 9, 2005 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Time Has Come Today Meredith must make an important choice about which path she wants to follow to determine the future of her love life. While she considers her future she and others have flashbacks of their pasts. Cristina spends time with Burke while he recovers. Webber and Adele have a conversation after he spends the night at the hospital. Everyone attempts to deal with Izzie's choice to quit. George seeks relationship advice from Derek. |
September 21, 2006 |
| 2 |
I Am a Tree Cristina meets Burke's parents, the interns try to get Izzie's job back, and Addison takes a day off, a surgical patient may be living her last day. Some of the interns want to know why Bailey won't talk to Izzie. Meredith tries to decide between Derek and Finn and comes to a decision somewhat. Webber finds out that Callie has been living in the hospital and he confronts her about it. |
September 28, 2006 |
| 3 |
Sometimes a Fantasy The staff tries to prevent a patient from getting an elective surgery. Cristina tries to help Preston cope with the after effects of his surgery. A patient bails on their surgery. Someone goes to a bed-and breakfast. Alex deals with a patient who has had a high amount of injuries in the past. A man undergoes surgery. Before the surgery his wife was only somewhat supportive, but the results may be too much for her to handle. Izzie tries to go back to the hospital for the first time since Denny died. One child's constant visits are noted by a nurse. Two foster patients are met with suspicions of child abuse. George and Callie's relationship moves forward. |
October 5, 2006 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
A Change Is Gonna Come Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her. |
September 27, 2007 |
| 2 |
Love/Addiction A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up to deal with what her son left behind. Lexie tries to talk to Meredith. Callie is overwhelmed by her new position while Bailey is searching for things to do. |
October 4, 2007 |
| 3 |
Let the Truth Sting The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is trying to deal with his guilt about having sex with Izzie. |
October 11, 2007 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Dream a Little Dream of Me (1) As Meredith and Derek begin to find that their "happily ever after" is anything but easy, Cristina develops a crush on a military doctor who brings in a trauma patient. Meanwhile, the Chief and his staff cope with the news that Seattle Grace is no longer considered a top-tier teaching hospital. |
September 25, 2008 |
| 2 |
Dream a Little Dream of Me (2) Alex is offended when Izzie talks about how great a man Alex is to Meredith. Derek is stabbed with the scalpel in the palm of his hand by Rose, while the Chief is stunned over Mercy West's increase in the number of patients, a deadly ice storm ravages Seattle. |
September 25, 2008 |
| 3 |
Here Comes the Flood When the plumbing springs a leak, chaos breaks out at Seattle Grace as the Chief tries to put in place new teaching methods. Meanwhile, George takes his residency exam; and Derek attempts to get Meredith's roommates to move out, much to their surprise. |
October 9, 2008 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Good Mourning The hospital staff is left to deal with the aftermath of George's passing. Hitting the staff hard, they all find unique ways to get through the various stages of grief. George's mom returns, faced with the difficult task of deciding what to do with his organs. |
September 24, 2009 |
| 2 |
Goodbye Everyone is struggling after losing one of their own and are turning to any distraction they can find. Meredith and Derek seem to be consummating their marriage anywhere and everywhere, while Cristina and Owen have been instructed to abstain from sex by Dr. Wyatt. |
September 24, 2009 |
| 3 |
I Always Feel Like Somebody's Watchin' Me Several weeks after her near-death experience, a recovering Izzie returns to work. Meanwhile, nervous that there will be layoffs in the hospital in the wake of an announcement from the Chief, the Seattle Grace residents compete to survive the cuts, including Cristina, who attempts to work alongside Arizona in pediatrics. And Bailey and Alex's patient's already complex case is further complicated by her schizophrenic son. |
October 1, 2009 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
With You I'm Born Again In the wake of the shooting at Seattle Grace-Mercy West, the doctors find themselves in a frenzy: Christina and Owen will be getting married, and others are trying to deal with the recent blood bath. Derek is arrested for speeding! |
September 23, 2010 |
| 2 |
Shock to the System Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won't let Alex operate until he has the bullet in his chest removed. |
September 30, 2010 |
| 3 |
Superfreak Issues surface when Derek's estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery. |
October 7, 2010 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Free Falling The fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital; April tries to step up to the plate as Chief Resident in the wake of a giant sinkhole in the middle of Seattle; and Cristina and Owen are still at odds over their drastically different feelings for their unborn child. |
September 22, 2011 |
| 2 |
She's Gone News of Meredith and Derek's unsteady relationship raises a red flag for Zola's adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out Meredith; and Cristina makes a tough decision regarding her unexpected pregnancy. Also, Chief Webber brings Henry in for a last minute surgery, alarming Teddy. This is an historic episode that finally crosses a long-standing barrier. |
September 22, 2011 |
| 3 |
Take the Lead The chief makes a decision that shocks everyone at Seattle Grace; Owen and Cristina attempt to find normalcy; April struggles in her new role; the 5th-year residents receive their first solo surgery assignments. |
September 29, 2011 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Going Going Gone The doctors of Seattle Grace are faced with the aftermath of last season's plane crash. As they try to move on with their lives, they must learn to adapt to the changes, cope with their losses and move forward with their relationships and careers. |
September 27, 2012 |
| 2 |
Remember The Time In this flashback episode, return to the site of the plane crash and watch as each doctor tries to cope with the heartache and injuries caused by the crash. Meanwhile, back at Seattle Grace, everyone struggles to find a bit of normalcy amidst the chaos. |
October 4, 2012 |
| 3 |
Love the One You're With The survivors from the crash are asked to make an almost impossible decision that will affect the rest of their lives. Meanwhile, tension grows between Jackson and April after they're forced to work together, and Alex tries to restrain himself with one of the interns. |
October 18, 2012 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Seal Our Fate The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already short handed ER to spring into action. Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona’s infidelity, and Richard’s life is in extreme danger. |
September 26, 2013 |
| 2 |
I Want You with Me Callie makes a decision about her relationship; the doctors receive devastating news. |
September 26, 2013 |
| 3 |
Everybody's Crying Mercy Derek and Meredith adjust to life at home with their newborn; Arizona tries to repair her marriage; Jackson and Owen clash over financial issues. |
October 3, 2013 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
I Must Have Lost It on the Wind With Cristina gone, a new doctor, Maggie Pierce, making the rounds and Derek wanting to move to Washington DC, Meredith struggles to regain a sense of normalcy both at home and in the hospital. Meanwhile, Callie and Arizona come to a decision about surrogacy, Amelia overhears a big secret, Bailey realizes she will have to fight Alex for Cristina’s board seat and a freak accident causes two teenagers to be caught in a very compromising position. |
September 25, 2014 |
| 2 |
Puzzle with a Piece Missing Maggie tries to make a good impression but finds herself in unfortunate situations; Richard keeps hiding his secret. |
October 2, 2014 |
| 3 |
Got to Be Real Owen tries to get Callie to help Veterans Hospital patients with the robotic limb lab. Alex and Meredith's friendship makes Jo jealous. Alex and Bailey prepare to go in front of the board. |
October 9, 2014 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Sledgehammer The doctors from Grey Sloan Memorial Hospital spring into action to save the lives of two girls with a powerful story. Meanwhile, Meredith tries to cope with the fact that Amelia is now living with her and Jackson prepares for April's return back to Seattle. |
September 24, 2015 |
| 2 |
Walking Tall The pressure is on as a determined Bailey tackles her first day as Chief; meanwhile, April's marriage is in jeopardy and she finds herself unable to address her problems; Meredith struggles to juggle all her responsibilities and Amelia works to define her relationship with Owen. |
October 1, 2015 |
| 3 |
I Choose You Maggie reevaluates her life choices after receiving an invitation to her ex-boyfriend’s wedding; Richard questions Bailey’s loyalty, and Jo confides in Stephanie about a secret she’s been keeping from Alex. Meanwhile, Alex struggles with making a difficult decision that will affect the lives of newborn twins. |
October 8, 2015 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Undo When one of Grey Sloan’s own lands in the hospital, Bailey tries to figure out what happened while the rest of the doctors jump in to help. Meredith juggles huge secrets that affect her relationships with Alex and Maggie. While Richard helps Jo with a big decision, April and Catherine clash over the new baby. |
September 22, 2016 |
| 2 |
Catastrophe and the Cure Meredith considers her loyalties, as Alex deals with the repercussions of his actions. Newlyweds Amelia and Owen host a dinner party with unlikely guests, and Jackson proposes an arrangement to help April through her recovery. |
September 29, 2016 |
| 3 |
I Ain't No Miracle Worker A car crash at a funeral brings a bickering family into the hospital. Back from New York, Arizona ends up caught between Alex and Andrew. While Ben takes on a new parenting role, Amelia helps Meredith and Maggie through a problem. |
October 6, 2016 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Break Down the House Meredith and the team are focused on helping Owen’s sister after her shocking return, and Amelia faces a conflict over a patient. Meanwhile, Bailey is forced to give Grey Sloan a facelift after the fire, and the doctors are introduced to a few new faces that spice things up around the hospital. |
September 28, 2017 |
| 2 |
Get Off on the Pain Meredith struggles to come up with a new plan for Owen’s sister. Jo makes a surprising choice regarding Alex, and Andrew’s sister’s controversial research leads to a shocking discovery. |
September 28, 2017 |
| 3 |
Go Big or Go Home Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith’s past returns as a patient, and Amelia tries to manage a secret. |
October 5, 2017 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
With a Wonder and a Wild Desire The doctors at Grey Sloan Memorial vie for a new position. Meredith is seemingly distracted and struggles to stay focused, and Maggie finds herself the keeper of a big secret while Amelia and Owen try to figure out their relationship. Meanwhile, Jo and Alex's honeymoon doesn't go exactly as planned. |
September 27, 2018 |
| 2 |
Broken Together New doctors continue to shake up the hospital in typical Grey Sloan manner. Meredith bonds with a patient while Jackson struggles with the meaning behind recent experiences; and after making a life-changing decision, Jo forms an unexpected alliance. |
September 27, 2018 |
| 3 |
Gut Feeling Meredith works on a patient who happens to specialize in matchmaking, and a seemingly drunk patient pushes Richard's buttons and gives him a medical mystery to solve. Meanwhile, Maggie tries to reach Teddy after bearing the burden of her secret becomes overwhelming as she struggles with issues in her own personal life. |
October 4, 2018 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Nothing Left to Cling To Meredith, Richard and Alex must deal with the consequences after Bailey fires them from Grey Sloan for insurance fraud. After disappearing in the fog, Jackson helps a man in a dangerous situation, as his relationship with Maggie comes to a new crossroad. Meanwhile, Tom gets new responsibilities at the hospital that throw the doctors for a loop. |
September 26, 2019 |
| 2 |
Back in the Saddle The doctors operate on a man who crashed into Maggie's car as Owen, back from paternity leave, struggles with Tom's new position. Meredith's recent firing doesn't stop her from diagnosing those around her. Richard and Alex start anew and it's not easy. |
October 3, 2019 |
| 3 |
Reunited A patient at the hospital is brain dead after falling into a construction site, and her two sisters must decide whether or not to keep her alive. |
October 10, 2019 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
All Tomorrow’s Parties The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic; an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment. |
November 12, 2020 |
| 2 |
The Center Won't Hold Bailey finds herself in the middle of an argument with patients' families as they await news about their children who were injured in a fire; Winston surprises Maggie; Amelia and Link try to have some fun as new parents. |
November 12, 2020 |
| 3 |
My Happy Ending The Grey Sloan doctors continue to face their new COVID-19 reality and deal with a familiar and stubborn patient. Koracick is put in charge of the interns who recently joined the hospital ranks and Link operates on a sex therapist. Elsewhere, Maggie finds comfort in Winston's virtual presence. |
November 19, 2020 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Here Comes the Sun (II) As the city of Seattle revels at the Phoenix Fair celebrating the city’s rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she’s having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother‘s past. The crossover starts on Station 19 S05E01 Phoenix from the Flame (I). |
September 30, 2021 |
| 2 |
Some Kind of Tomorrow Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure. |
October 7, 2021 |
| 3 |
Hotter Than Hell Seattle’s favorite redhead returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents. Meanwhile, Meredith has a decision to make, and Link confides in Teddy. |
October 14, 2021 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Everything Has Changed After a long six months, Grey Sloan Memorial has reinstated its residency program. A group of talented and striving young interns has been recruited as the attending surgeons work to rebuild the program to its former glory. Meredith, still functioning as the interim chief, sees Nick for the first time since she rejected his offer to move to Minnesota. Meanwhile, Bailey tells Richard she is not ready to return to work. Levi works up the courage to break disappointing news to Jo, and things turn awkward when Link realizes he has met one of the interns already. With Amelia and Maggie’s help, the new doctors are thrown into their first day on the job dealing with injuries from a recent tornado. |
October 6, 2022 |
| 2 |
Wasn't Expecting That The attending surgeons and interns work together to solve a medical mystery when a college kid comes in with what first looks like food poisoning but has escalating and dire complications. Meanwhile, Jo spends her day off with Bailey. |
October 13, 2022 |
| 3 |
Let's Talk About Sex Bailey recruits the interns to create a series of social media videos informing teens about sexual health. The videos, filmed at Grey Sloan in front of a group of high schoolers, hit home as a student has medical complications during her visit. Elsewhere, Meredith and Maggie learn something new about Zola. |
October 20, 2022 |
Production
Release
| Original network/platform | ABC |
|---|---|
| First aired | March 27, 2005 |
| Last aired | May 7, 2026 |
| Status | Returning Series |
| Schedule | Thursday at 22:00:00 |