Series synopsis
St. Denis Medical is an American comedy television series that premiered on NBC on November 12, 2024. It was created by Justin Spitzer, Eric Ledgin. It stars Wendi McLendon-Covey, Allison Tolman, Josh Lawson and Kahyun Kim.
An eclectic group of underfunded yet dedicated doctors and nurses navigates caring for patients — and each other — while keeping it all together at an Oregon hospital.
Premise
An eclectic group of underfunded yet dedicated doctors and nurses navigates caring for patients — and each other — while keeping it all together at an Oregon hospital.
Premise: It's quite the operation.
Cast and characters
Leading cast
- Wendi McLendon-Covey as Joyce Henderson
- Allison Tolman as Alex Mazurkian
- Josh Lawson as Bruce Schweitz
- Kahyun Kim as Serena Jung
- Mekki Leeper as Matt Pearson
- Kaliko Kauahi as Val
- David Alan Grier as Ron Leonard
- Mindy Sterling as Laurie
Supporting cast
- Betsy Sodaro as Female Patient
- Feodor Chin as Phil
- Mike Park as Doctor #1
- Minita Gandhi as Doctor #2
- Robert Arce as Male Patient
- Alan Barinholtz as Walter Schroeder
- Joe Keyes as Mr. Taylor
- Lita Lopez as Nurse Crystal
- Scott Subiono as Older Man
- Michelle Haro as Swollen Patient
- Jackie Brougham as Waiter
- Christina Miller as Dr. Miller
Guest cast
- Mindy Sterling as Laurie
- Betsy Sodaro as Female Patient
- Feodor Chin as Phil
- Mike Park as Doctor #1
- Minita Gandhi as Doctor #2
- Robert Arce as Male Patient
- Alan Barinholtz as Walter Schroeder
- Joe Keyes as Mr. Taylor
- Lita Lopez as Nurse Crystal
- Scott Subiono as Older Man
- Michelle Haro as Swollen Patient
- Jackie Brougham as Waiter
Episodes
This series spans 3 seasons with 37 episodes.
| Season | Episodes | First aired | Last aired |
|---|---|---|---|
| Season 1 | 18 | November 12, 2024 | April 29, 2025 |
| Season 2 | 18 | November 3, 2025 | April 6, 2026 |
| Season 3 | 1 | November 2, 2026 | November 2, 2026 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Welcome to St. Denis Alex is torn between her daughter's school play and an "all-hands" situation in the Emergency Department. Joyce spends the hospital's limited funds on a fancy mammography machine. Matt's first day as a nurse isn't going as he'd hoped. |
November 12, 2024 |
| 2 |
A Very Robust Personal Life Joyce's belief that personal life should stay out of the workplace is tested by unexpected news. Ron thinks a patient has a crush on him. Bruce tries to demonstrate the value of his important work. |
November 12, 2024 |
| 3 |
Weird Stuff You Can't Explain When Ron hexes the day to prove superstitions aren't real, things at the hospital start getting weird. Joyce and Matt discover an employee's secret. |
November 19, 2024 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Aloha, Everyone Alex tries to hold on to her peaceful vacation vibes. Joyce faces a design crisis in the birthing center. Matt and Serena reassess their working relationship. |
November 3, 2025 |
| 2 |
Mama Bear Activated After Bruce is attacked at the hospital, Matt helps him deal with the aftermath. Alex motivates Joyce to amp up security, while Ron and Serena debate who is more qualified to defend themselves. |
November 3, 2025 |
| 3 |
Get Me in the Pod, Brother Alex and Ron spar over the wisdom of open communication. Joyce brings in a body scanner that proves overly distracting. |
November 10, 2025 |
| Episode | Title | Air date |
|---|---|---|
| 1 | Episode 1 | November 2, 2026 |
Production
Release
| Original network/platform | NBC |
|---|---|
| First aired | November 12, 2024 |
| Last aired | April 6, 2026 |
| Runtime | 22 minutes |
| Status | continue |
| Schedule | Monday at 20:00:00 |