Series synopsis
Common Side Effects is an American animation drama comedy sci-fi & fantasy television series that premiered on Adult Swim on February 2, 2025. It was created by Joseph Bennett, Steve Hely. It stars Dave King, Emily Pendergast, Mike Judge and Martha Kelly.
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Premise
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Cast and characters
Leading cast
- Dave King as Marshall Cuso (voice)
- Emily Pendergast as Frances Applewhite (voice)
- Mike Judge as Rick Kruger (voice)
- Martha Kelly as Agent Harrington (voice)
- Joseph Lee Anderson as Agent Copano (voice)
- Alan Resnick as Zane (voice)
- Lin Shaye as Sonia (voice)
- Andy Daly as Mysterious Passenger (voice)
Supporting cast
- Shalita Grant as Susan (voice)
- Bob Stephenson as Connor (voice)
- Nicolas Cantu as Tommy (voice)
- Timothy Simons as Lawyer (voice)
- Jon Foor as Hoang (voice)
- Sydney Tamiia Poitier as Cecily (voice)
- Sue Rose as Hildy (voice)
- Shannon Woodward as Amelia (voice)
- Danny Huston as Jonas Backstein (voice)
- Ben Feldman as Nick (voice)
- Steve Hely as Rusty (voice)
- Christine Ko as Kiki (voice)
Guest cast
- Alan Resnick as Zane (voice)
- Lin Shaye as Sonia (voice)
- Andy Daly as Mysterious Passenger (voice)
- Shalita Grant as Susan (voice)
- Bob Stephenson as Connor (voice)
- Nicolas Cantu as Tommy (voice)
- Timothy Simons as Lawyer (voice)
- Jon Foor as Hoang (voice)
- Sydney Tamiia Poitier as Cecily (voice)
- Sue Rose as Hildy (voice)
- Shannon Woodward as Amelia (voice)
- Danny Huston as Jonas Backstein (voice)
Episodes
This series spans 2 seasons with 10 episodes.
| Season | Episodes | First aired | Last aired |
|---|---|---|---|
| Season 1 | 10 | February 2, 2025 | March 30, 2025 |
| Season 2 | 0 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Pilot Marshall meets his old high school classmate Frances and lets her in on a world-changing secret. |
February 2, 2025 |
| 2 |
Lakeshore Limited Marshall's forced on the run as the DEA pursues him. |
February 2, 2025 |
| 3 |
Hildy Marshall visits an old mentor as new pressures mount. |
February 9, 2025 |
Production
Release
| Original network/platform | Adult Swim |
|---|---|
| First aired | February 2, 2025 |
| Last aired | March 30, 2025 |
| Runtime | 23 minutes |
| Status | continue |
| Schedule | Sunday at 23:30:00 |