Series synopsis
The Twisted Tale of Amanda Knox is an American drama television series that premiered on Hulu on August 20, 2025. It ended on October 1, 2025. It was created by K.J. Steinberg. It stars Grace Van Patten, Sharon Horgan, Francesco Acquaroli and Giuseppe De Domenico.
Amanda Knox arrives in Italy for her study abroad only to be wrongfully imprisoned for murder weeks later. Follow Knox's relentless fight to prove her innocence and reclaim her freedom and examines why authorities and the world stood so firmly in judgment.
Premise
Amanda Knox arrives in Italy for her study abroad only to be wrongfully imprisoned for murder weeks later. Follow Knox's relentless fight to prove her innocence and reclaim her freedom and examines why authorities and the world stood so firmly in judgment.
Premise: Does the truth exist if no one believes it?
Cast and characters
Leading cast
- Grace Van Patten as Amanda Knox
- Sharon Horgan as Edda Mellas
- Francesco Acquaroli as Giuliano Mignini
- Giuseppe De Domenico as Raffaele Sollecito
- John Hoogenakker as Curt Knox
- Roberta Mattei as Valentina Greco
- Joe Lanza as Chris Mellas
- Anna van Patten as Deanna Knox
Supporting cast
- Corinna Locastro as Ginevra Ferrari
- Fabio Salerno as Bruno Ricci
- Alfredo Pea as Don Saulo Scarabattoli
- Stefano Cassetti as Carlo Della Vedova
- Federico Tocci as Luciano Ghirga
- Evelyn Famà as Lucrezia Ippolito
- Souleymane Seye Ndiaye as Patrick Lumumba
- Viktorija Portnova as Aleksandra Lumumba
- Cecilia Dazzi as Giulia Bongiorno
- Vincenzo De Michele as Ettore Banti
- Mariagrazia Pompei as Manuela Comodi
- Rhianne Barreto as Meredith Kercher
Guest cast
- Giuseppe Lo Piccolo as Edoardo Leone
- Sara Sedran as Kenzie Vidal
- Grace Coulson-Harris as Sophie Purton
- Favia Leone as Benedetta Mignini
- Ilenia D'Avenia as Gregora
- Giulia Innocenti as Mara Papagni
- Massimiliano Caprara as Inspector Giordano
- Lorenzo Lancellotti as Rocco De Luca
- Marco Iermanò as Daniele
- Barbara Smith as Amy Frost
- Isidora Fairhurst as Samantha Rodenhurst
- Tommaso Sacco as Reporter
Episodes
This series spans 1 season with 8 episodes.
| Season | Episodes | First aired | Last aired |
|---|---|---|---|
| Season 1 | 8 | August 20, 2025 | October 1, 2025 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Amanda American college student, Amanda Knox, embarks on her study abroad trip in Italy. The morning before Amanda is supposed to leave on a romantic excursion with her new Italian boyfriend, Raffaele Sollecito, things take a sinister turn. |
August 20, 2025 |
| 2 |
Ci vediamo più tardi ("See you later") Under mounting pressure, the police try to break Amanda and Raffaele while Edda races to reunite with her daughter. |
August 20, 2025 |
| 3 |
The Guardian of Perugia As Amanda, Raffaele, and Patrick Lumumba enter prison, Giuliano Mignini, their prosecutor, continues to build his case against them while the media's reporting turns Amanda into a monster. |
August 27, 2025 |
Production
Release
| Original network/platform | Hulu |
|---|---|
| First aired | August 20, 2025 |
| Last aired | October 1, 2025 |
| Status | ended |
| Schedule | Wednesday |