Series synopsis
Most Extreme Humans is an American reality television series that premiered on TLC on June 10, 2026.
Explores the lives of people with extraordinary physical conditions, rare medical challenges, and remarkable transformations as they navigate everyday life, relationships, and the pursuit of their dreams.
Premise
Explores the lives of people with extraordinary physical conditions, rare medical challenges, and remarkable transformations as they navigate everyday life, relationships, and the pursuit of their dreams.
Episodes
This series spans 1 season with 4 episodes.
| Season | Episodes | First aired | Last aired |
|---|---|---|---|
| Season 1 | 4 | June 10, 2026 | August 12, 2026 |
| Episode | Title | Air date |
|---|---|---|
| 1 |
Biggest Hands Mark's hands are 20 times bigger than a normal adult male's. After learning that his condition may require amputation, Mark stopped seeing doctors. Now troubling changes to his hands means he must go back. If not for himself, then for his young daughter. |
June 10, 2026 |
| 2 |
Ugliest Man Winner of the Uganda's Ugliest Man contest, Godfrey has a disorder that has left him disfigured. |
June 17, 2026 |
| 3 |
Upside Down With a Twist In Brazil, Claudio lives with a condition that bent his head backward. |
June 24, 2026 |
Production
Release
| Original network/platform | TLC |
|---|---|
| First aired | June 10, 2026 |
| Last aired | June 24, 2026 |
| Status | continue |
| Schedule | Wednesday at 21:00:00 |