Casualty

Rushing to attend the birth of his child, a fuel tanker driver crashes into Holby General's Acute Assessment Unit. Immediate evacuation of the hospital has begun as the tanker leaks petrol into the hospital basement. The driver's wife delivers a mixed-race son who is identifiably the result of an extra-marital affair. The driver dies unaware of his wife's infidelity, and as the baby begins to experience breathing difficulties, his mother rejects him. Connie Beauchamp and Alistair Taylor are forced to complete open heart surgery on a child as the evacuation continues, held hostage by the child's father. Paramedic Luke Warren fails to spot the deadly symptoms of a student with Lassa fever, and receptionist Bex Reynolds is lured up to Nightingale Wing pharmacy by a fake pharmaceutical representative. As the generator is switched off in the basement, the petrol explodes and the Nightingale building bursts into flames, trapping numerous staff members inside.

As firefighters struggle to contain the aftermath of the explosion, Connie is joined in theatre by Harry as they continue the transplant by torchlight. Rosie and Jim manage to get the baby to safety, but as debris falls, Rosie is impaled on a piece of metal. Bex is discovered by firemen and carried to safety. Alistair abandons the transplant and jumps from a fifth floor window. Critically injured, he talks nurse Donna Jackson through a life saving procedure on another patient before dying. From outside, Ric Griffin guides Connie to a maintenance corridor and bridge which will lead those trapped to a point where firefighters are waiting for them. Suddenly, the fake pharmaceutical representative rushes across behind them, damaging the bridge further and falling to his death. Jim and Rosie are left hanging from the broken bridge holding on to one of Harry's arms each. Knowing Harry will be unable to hold both their weight for much longer, Jim saves Rosie's life by letting go.

A gas explosion at the docks causes a rush of casualties choking on the fumes, but can an antidote be found in time?

A hysterical woman who threatens to kill a baby tests Baz's patience and ability to the limit.

A policeman is stabbed at a local football fixture, but is the situation as simple as it seems? A Christian Scientist's beliefs puts her life at a risk.

Paramedic Josh becomes implicated in a motorcycle accident whilst off duty. Consultant Julian Chapman has to face the boy's distraught dad Bill and sister Lucy. Meanwhile, Charlie clashes Dr Robert Khalefa when he hands out unwanted medical advice about a patient with stomach pains. Duffy's also in a difficult situation and has to tread carefully.

Family loyalties are stretched to breaking point when a young tearaway is forced to choose between saving his brother and freedom. And Charlie has a decision to make which will change his future – and that of the department. Matt joins the staff on the reception desk and Josh, now manning a motorbike, has a fight on his hands, trying to save a young tearaway's brother but he dies later, of his injuries. The staff are shocked when they find a stab victim has sold one of her kidneys and she now faces kidney failure.

Tensions run high in Holby as foot-ball fans gather for the Saturday match. For Kevin, a rookie policeman, the simple arrest of a drunk biker has tragic consequences. Meanwhile, a disabled young girl poses a challenge for new nurse Jude. The arrested biker arrives at Holby with symptoms of being drunk but tests reveal he has a brain tumour of which he dies of later. A disabled young girl confides to Jude that she has a sexual relationship unknown to her mother. Dr Eddie Gordon and Nurse Kate Wilson disagree over involving Social Services with an asthmatic mother and her home alone daughter.

A horrifying chain of events begins to unravel after Rachel is the victim of a disturbed patient. A case of sexual harassment by her brother-in-law is uncovered when a woman appears anxious about her job. Tragedy strikes a couple who are mugged, when the man dies and then the woman tells Ash, although they lived as man and wife, they were in fact brother and sister. Mike Barratt finally admits to Charlie that his wife has left him and taken the kids. An elderly woman is found dead and her daughter is brought in with stab wounds. A mentally disturbed patient is recognised as the missing daughter, who killed her mother and stabbed her sister. When she tries to kill herself, Charlie comes to the rescue and talks to her. She reveals how her family made her life hell and she just snapped.

Jack is now engaged to Jayne but overreacts when new nurse Tina Seabrook makes an unfortunate comment about a man who deliberately fell off a ladder to get into hospital. Josh and Liz try to get Ian and Esme, a couple who are having a baby to the hospital, but end up having to deliver the baby in the back of an ambulance. Young black couple Jason and Lou are arguing about her desire to join the police, who Jason sees as institutionally racist. After they part ways, Jason sees someone park a van in the car park at a shopping centre. A bomb in the van goes off, causing many casualties. An elderly man removes glass imbedded in his wife's stomach and she dies of internal bleeding. Lou seems to have minor injuries but in hospital a scan shows she has a bleed on the brain, which leaves her in a coma. Ian has been left trapped in rubble and when a second bomb is discovered Baz and Josh amputate his foot to get him out.

An underage prostitute, Lucy, is lured to a garage by a client where she is beaten up by a group of men and dumped outside the hospital. Jack warns George about getting too involved in the case. Lucy's friend Julie turns up and it transpires she set up the beating because Lucy was planning on quitting the game. Lucy initially leaves with Julie but later returns to see George. Liz argues with her husband John, who thinks she is not spending enough time at home. A young woman brings in her older neighbour; they are involved in a dispute over a fence and the older woman tripped over. Sam manages to get them talking. A young man with a history of mental health issues pushes his mother (Brigit Forsyth) down the stairs. Richard and Kate convince her to have him sent to a psychiatric hospital.

Life hangs in the balance for Josh and Finlay when their ambulance crashes dramatically into a railway bridge. And the arrival of Duffy's baby is imminent.

An angst-ridden Josh is in even hotter water when he comes face-to-face with the sister of the boy he killed, and Colette's teenage daughter announces she's pregnant.

New doctor Lara Stone is thrown straight in the deep end. Charlie meets the new chief executive in unexpected circumstances - a supper club for singles!

Three months on, Nikki returns to work and finds the experience still haunts her and has to deal with a stabbing victim on her first shift. Jack is embarrased when she finds out about his spontaneous marriage proposal by her bedside. While taking his children out to the fair, Harry finds himself on-duty after a helicopter crash and is forced to deal with the injured as well as deal with his rebellious daughter. He feels guilty when he finds his heroic actions have infact cost lives. After being arrested, Lara is terrified for her future and looks to David's wife to verify her story in court.

Lara begins her court trial and suffers flashbacks and the bad memories associated with her assault. New SHO locum Heather Lincoln arrives and doesn't go unnoticed by Simon, who gives her a guided tour – Colette teases ‘Does the tour include the cold showers?'. Later Dillon unwittingly starts to undress in the staff room, unaware Heather is enjoying the view. Heather, is quick to forget about a drink with Simon after shift, and is about to proposition Dillon, when Simon walks in. Heather gets Duffy's back up by bluffing her way through a patient's case and getting Harry on her side – and Duffy becomes more unhappy when her mother is brought in to the department, seriously ill with breast cancer. Finn is unhappy when he finds he is named in Comfort's divorce papers.

It's the day of Lara's trial, but she's not feeling positive since Melanie Collier denied her husband raped her. Lara tries to convince the jury her act was self-defence. Lara is shocked, when they return their verdict. While Duffy is in court, her mother, Kate, is brought in after her condition worsens. Kate tells Charlie she wishes not to be resuscitated. Duffy is angered by Charlie's attempts at sympathy and finds a shoulder to cry on in new security guard Ryan. Dillon and Harry clash with Charlie over how to treat two sisters, who are found to be drug mules.

The consequences of the train crash begin to hit home. Comfort struggles to come to terms with what has happened. And Jim warns Nikki not to get involved with Paul.

Two children go missing and suspicion falls on a local convicted paedophile, while Abs is still reeling from Simon's death.